Antenatal maternal factors and optic nerve hypoplasia

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Maternal anticonvulsants and optic nerve hypoplasia.

Seven patients with optic nerve hypoplasia, born of epileptic mothers, are presented. All the mothers took anticonvulsants during pregnancy. The possibility that maternal anticonvulsant therapy may play a role in the genesis of optic nerve hypoplasia is discussed in the light of what is known about the teratogenicity of these agents.

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Optic nerve hypoplasia: Risk factors and epidemiology.

OBJECTIVES To study the epidemiology of optic nerve hypoplasia. DESIGN AND METHODS Children with optic nerve hypoplasia and visual impairment were identified through the Swedish Register of Visually Impaired Children. Pre- and perinatal characteristics were obtained from the Medical Birth Registry and by scrutinizing pregnancy and delivery records. Clinical characteristics of children with op...

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Spectrum of optic nerve hypoplasia.

Optic nerve hypoplasia is a non-progressive condition characterised by subnormal vision and a subnormal number of optic nerve axons. It may be unilateral or bilateral, isolated or combined with other defects. Analysis of fundus photographs from a series of 7 patients with a stationary abnormality of different degrees showed that the functional defects could be closely correlated with defects in...

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Hypoplasia of the optic nerve.

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ژورنال

عنوان ژورنال: Eye

سال: 1991

ISSN: 0950-222X,1476-5454

DOI: 10.1038/eye.1991.142